Autoimmune thyroid disease and associated autoimmunity

Autoimmunity and autoimmune disease

Autoimmune thyroid diseases and nonorgan‑specific autoimmunity.

Autoimmune thyroid diseases (ATD), as the most common organ‑specific autoimmune disorder, is frequently accompanied by other organ- and nonorgan‑specific autoimmune diseases. Although the exact pathogenic mechanism of the coexistence of autoimmune disorders has not been clearly defined, genetic and environmental factors, immune defects, and hormonal changes, may play a key role in polyautoimmun...

Celiac Disease Autoimmunity in Patients with Autoimmune Diabetes and Thyroid Disease among Chinese Population

The prevalence of celiac disease autoimmunity or tissue transglutaminase autoantibodies (TGA) amongst patients with type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) in the Chinese population remains unknown. This study examined the rate of celiac disease autoimmunity amongst patients with T1D and AITD in the Chinese population. The study included 178 patients with type 1 diabetes and...

Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Thyroid Autoimmunity

The autoimmune/inflammatory syndrome induced by adjuvants (ASIA), presented by Shoenfeld and Agmon-Levin in 2011, is an entity that incorporates diverse autoimmune conditions induced by the exposure to various adjuvants. Adjuvants are agents that entail the capability to induce immune reactions. Adjuvants are found in many vaccines and used mainly to increase the response to vaccination in the ...

CXC-Chemokines and Thyroid Associated Autoimmunity

Chemokines are a group of peptides of low molecular weight that induce the chemotaxis of different leukocyte subtypes [1]. The major function of chemokines is the induction of leukocyte migration to inflammation sites, but they also play a role in tumoral growth, in angiogenesis and in organ sclerosis [2]. At the present more than 50 chemokines have been described, which can be classified in 4 ...